博莱纹身是一种很有希望的治疗方法在大瘢痕疙瘩及肥厚性疤痕.

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背景:冷冻合并intralesional舒松注射是最常见的传统疗法瘢痕和瘢痕疙瘩. The literature contains few articles on the use of bleomycin tattoo for treatment of these conditions.文学包含数篇关于使用博莱纹身治疗这些条件. OBJECTIVE: This study compares the efficacy of bleomycin tattoo with that of cryotherapy combined with intralesional triamcinolon injection for the treatment of keloids and hypertrophic scars.目标:这项研究比较了功效博莱文身与冷冻联合intralesional舒松注射治疗瘢痕疙瘩及肥厚性疤痕. MATERIALS AND METHODS: Forty-five patients with hypertrophic scars or keloids were randomly divided into two groups.材料和方法:45例肥厚性疤痕或蟹足肿,随机分成两组. Group A was treated with bleomycin tattoo, and group B, with cryotherapy combined with intralesional triamcinolon injection.对照组博莱纹身,B组,与冷冻联合intralesional舒松注射. There were four therapeutic sessions at 1-month intervals.共有四种治疗时段在1个月的时间间隔. All patients were followed for 3 months after the end of treatment.所有病人均在治疗结束后3个月的治疗. RESULTS: Therapeutic response in lesions less than 100 mm2 was higher than 88% in both groups, but in larger lesions, the therapeutic response to bleomycin was significantly better than cryotherapy combined with intralesional triamcinolon injection (p = .03).结果:治疗反应病变小于10012/30,高于88%,两组但在较大的病变,治疗反应博莱明显优于冷冻疗法结合intralesional舒松注射(P值为217.03). In group A, no relationship was observed between therapeutic response and lesion size (p = .58); however, in group B smaller lesions (< 100 mm2) displayed better therapeutic response (p = .007).在A组,无相关性的治疗反应和病变大小(P值为183.58);不过,在B组较小病变("10012/30)显示有较好的治疗反应(p=0.007). CONCLUSIONS: Bleomycin tattoo may be more effective than cryotherapy combined with intralesional triamcinolon injection in treatment of larger keloids and hypertrophic scars (size > 100 mm2).结论:博莱纹身可能要比冷冻联合intralesional舒松注射治疗较大瘢痕疙瘩和增生疤痕. 皮肤科,伊斯法罕大学医学科学院,伊斯法罕,伊朗. (国外文献)