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发表于 2015-5-19 15:13:35 | 显示全部楼层 |阅读模式
Treat Acne Scarring----痤疮疤痕的治疗

搬运国外的文章,用自动翻译大概翻译了一下,以方便大家的阅读,不保证翻译质量~
仅供参考,以下是正文,按照一段原文,一段翻译文排列。

Scars are areas of fibrous tissue (fibrosis) that replace normal skin after injury. A scar results from the biological process of wound repair in the skin and other tissues of the body. With the exception of very minor lesions, every wound (e.g. after accident, disease, surgery) results in some degree of scarring. Scar tissue is the same protein (collagen) as the tissue that it replaces, but the fiber composition of the protein is different. Instead of a nice “basket weave” formation of fibers, the collagen in scar tissue is aligned in a single direction resulting in a pronounced and thicker appearance. Acne treatments for most are long term and can result in scarring. There are multiple causes of acne including hormone dysfunction, allergies, environmental factors and nutrition deficiencies. Acne scars result after skin follicles become blocked by excessive oils and the physiology of keratin and old skin cells trigger an inflammatory response reaction. The skin will attempt to heal and the scar tissue results as the collagen becomes deformed and thickens. Acne scars are categorized as being “ice- pick”, “rolling” or “boxcar.”
疤痕是取代正常皮肤损伤后纤维组织(纤维化)地区。疤痕的结果从创伤修复中的皮肤和身体的其他组织中的生物学过程。除了非常轻微病变,伤口每次(例如,事故,疾病,手术后)的结果在一定程度上疤痕。瘢痕组织是因为它取代了组织相同的蛋白质(胶原蛋白),但该蛋白的纤维组成是不同的。的一个很好的“织篮”形成纤维代替,瘢痕组织在胶原蛋白中产生了显着的和较厚的外观的单方向取向。治疗痤疮大多数是长期,并可能导致疤痕。有痤疮的多种原因,包括激素功能紊乱,过敏症,环境因素和营养缺陷。皮肤毛囊成为阻止过多的油和角蛋白和老年皮肤细胞的生理学后痤疮疤痕导致触发炎症应答反应。皮肤将尝试愈合和瘢痕组织的结果作为胶原产生变形和变稠。痤疮疤痕被归类为“冰锥”,“滚动”和“棚车。”

How to treat acne scars/ surgical scars.
如何治疗痤疮疤痕/手术疤痕。

The Dermapen treatment can provide drastic results improving the appearances of the scars. The micro needles of the Dermapen® create new collagen and elastin to be generated and deposited called collagenesis, however the added benefit of new capillary growth is also a result which can improve blood supply to the area which helps create healthier existing skin as well as provide a healthy foundation for the new skin. The physical nature of “skin-needling” breaks up this fibrous and uneven scar tissue and stimulates the growth of new tissue. Currently there are ablative and non-ablative treatments offered which can damage the epidermis and evaporate the skin leading to thinner epidermis problems. The Dermapen® keeps the epidermis integrity full intact while treating the area which quickens healing time and causes less pain.
电动微针治疗可提供疤痕大幅改善的结果的出现。要生成的电动微针的微针创建新的胶原蛋白和弹性蛋白和沉积称为人类自体胶原,然而新的毛细血管生长额外的好处也是其结果是可以改善的血液供应,这有助于创建健康存在的皮肤的区域,以及提供新的皮肤健康的基础。“皮肤针刺”的物理性质打破了这种纤维和不均匀的疤痕组织,刺激新组织的生长。目前有提供烧蚀和非燃烧的治疗可能损坏表皮和蒸发导致更薄表皮问题的皮肤。电动微针可保持表皮完整的充分完整,同时把它加快愈合时间,并导致痛苦少的区域。

How many treatments?
需要多少次治疗?

Your medical professional should consult on medical treatment. While each patient is different and conditions will vary, the typical treatment regimen will consist of 5-6 treatments.
您应该咨询专业医疗人员。而每个患者都是不同的,条件是变化的,典型的治疗方案将包括5-6治疗。

Acne Scars: Over 90% of adolescents have acne and 1% of the population have acne scars.
痤疮疤痕:超过90%的青少年有粉刺和有1%的人有痤疮疤痕。  

Why Acne Scars?  Acne scars are created by the wound healing process occurring after the acute process of inflammation, follicular rupture and perifollicular abscess formation.  
痤疮疤痕怎么产生的? 痤疮疤痕由炎症,滤泡(发炎肿大的毛囊)破裂和毛囊周围脓肿形成的急性处理后发生的伤口愈合过程中产生的。  

Types of Acne Scars.  The resulting acne scars may be atrophic or hypertrophic (Fabbrocini et al., 2010).  Approximately 80% of scars are atrophic associated with a net loss of collagen during the matrix remodeling process.  A minority of scars are hypertrophic or have keloid formation.  Atrophic scars are classified as:
痤疮疤痕的类型。由此产生的痤疮疤痕可能萎缩或增生(Fabbrocini et al., 2010)。大约80%的疤痕是与胶原蛋白在基质重塑过程的净损失相关萎缩。疤痕少数有肥厚,或有瘢痕疙瘩的形成。萎缩性疤痕分类为:

Ice pick (70%) – These are the narrow < 2mm punctiform depressions with a “V” cross-section.
冰凿(70%) - 这是狭窄<2毫米点状凹陷带“V”的横截面。  

Boxcar (20%) – These are round or oval scars with well-established vertical edges with a wide base and a “U” cross-section.
棚车(20%) - 这些是圆形或椭圆形的伤痕与具有宽基座和一个“U”形横截面既定垂直边缘。

Rolling scars (10%) – These wide > 4 mm scars have an “M” cross-section and give an undulating appearance to the skin.
轧制伤痕(10%) - 这些宽“4毫米伤痕具有”M“的横截面,并给予一个起伏的外观的皮肤。


痤疮疤痕的治疗
痤疮疤痕等级1 ,症状:黄斑,临床特点:红斑高血糖或低色素平痕。这些不存在的轮廓缺陷,而是色差问题。
痤疮疤痕等级2 ,症状:温和,临床特点:轻度萎缩或肥厚疤痕并不明显,在>50厘米深度和可能受化妆或面部毛发所遮盖。
痤疮疤痕等级3 ,症状:温和,临床特点:中度萎缩性或增生性疤痕是明显的在>50厘米的深度,无法被化妆品或面部毛发所遮盖。痘坑可以通过手动皮肤伸展展平。
痤疮疤痕等级4 ,症状:严重,临床特点:重度萎缩性或增生性疤痕是明显的在>50厘米的深度,无法被化妆品或面部毛发所遮盖。痘坑不会通过手动皮肤伸展展平。

Acne Scar Treatments There are many treatments for acne scars, each with characteristic side effects. For most treatments, the principle treatment side effect is postinflamatory hyperpigmentation (Fabbrocini et al., 2010) which is most pronounced in darker skin types (Shah and Alexis, 2010). Postinflammatory hyperpigmentation may result from dermabrasion, chemical peels and laser resurfacing.
痤疮疤痕治疗有许多方法,各有特色和副作用。对于大多数治疗方法,在治疗上副作用是炎症后色素沉着(Fabbrocini et al., 2010),这是最明显的肤色较深的类型(Shah and Alexis,2010)。皮肤磨削术,化学换肤和激光换肤可能导致炎症后色素沉着。


痤疮疤痕的治疗
处理类型:化学剥脱                        
机制 - 指示:最好的结果与黄斑疤痕。唯一的变数结果与冰锥和滚动疤痕。   
副作用:暂时色素沉着或刺激。
处理类型:皮肤磨削术
机制 - 指示:彻底消除了表皮的乳头状或网状真皮层。将把冰锥和滚动疤痕。   
副作用:全身麻醉和感染的风险。显著患者的停机时间。肤色较深的可能会褪色和斑点。
处理类型:微晶磨皮术
机制 - 指示:除去表皮的外层。没有深深的伤痕。
副作用:只有罕见的并发症。
处理类型:电动微针
机制 - 指示:表皮基本完好,6周的作用机制后,看到全效提高胶原蛋白的产生。
副作用:炎症后色素沉着比其他程序的风险最低。
处理类型:CO2点阵激光治
机制 - 指示:烧蚀比非烧灼性更有效。40~80%的痕深度量化的改善。
副作用:病人必须停止异维A酸使用。黝黑的皮肤是炎症后色素沉着的风险。采用传统的共色素沉着2 激光为36%(阿尔斯特和西部,1996年)

Dermapen Treatment of Acne Scars.  The Dermapen is a convenient and effective way of performing needle dermabrasion.
电动微针治疗痤疮疤痕。电动微针是执行针磨皮的一种方便和有效的方法。  

The Dermapen adjustable needles penetrate a controlled depth into the dermis.  The dermis develops multiple microbruises, which start a cascade of growth factor release and collagen production.  Punch biopsy histology demonstrates thickening of the skin with dramatic increases in new collagen and elastin fibers (Fabbrocini et al., 2010).  As collagen is deposited, the skin texture improves.  Results are initially seen in six weeks and full effect will take three months to develop.  
电动微针可调针穿透的受控深度进入真皮。真皮开发多种微创伤,其开始生长因子释放和胶原蛋白的产生的级联。穿刺活检组织学证实与急剧增加新的胶原蛋白和弹性纤维皮肤增厚(Fabbrocini等,2010)。胶原沉积,皮肤纹理得到改善。结果最初出现在六个星期,全部效果将需要三个月来养护。

Severity grade of rolling scars has been shown to be statistically reduced in a clinically meaningful fashion after two sessions of needle dermabrasion (Fabbrocini et al., 2009).  Importantly, there was no sign of hyperpigmentation in the 32 patients studied.
强度等级的轧制伤痕已显示在具有临床意义的方式进行统计减小针磨皮的两个会话(Fabbrocini et al., 2009)之后。重要的是,在32例患者的研究没有任何有色素沉着的迹象。

References
参考
Alster TS, West TB (1996) Resurfacing of atrophic facial acne scars with a high-energy, pulsed carbon dioxide laser.  Dermatol Surg 22: 151-155.
Camirand A, Doucet J (1997) Needle dermabrasion.  Aesthetic Plast Surg 21: 48-51.
Fabbrocini G, Fardella N, Monfrecola A, Proietti I, Innocenzi D (2009) acne scarring treatment using skin needling.  Clin Exp Dermatol 34: 874-879.
Fabbrocini G, Annunziata MC, D’Arco V, De Vita V, Lodi G, Mauriello MC, Pastore F, Monfrecola G (2010) Acne scars:  Pathogenesis, classification, and treatment.  Dermatol Res Pract 2010: 893080.
Goodman G (2003) Post acne scarring: a review.  J Cosmet laser Ther 5: 77-95.
Goodman GJ, Baron JA (2006) Post acne scarring: a qualitative global scarring grading system.  Dermatol Surg 32: 1458-1466.
Graber EM, Tanzi EL, Alster TS (2008) Side effects and complications of fractional laser photothermolysis: experience with 961 treatments.  Dermatol Surg 34:
301-305.
Jacob CI, Dover JS, Kaminer MS (2001) acne scarring: a classification system and review of treatment options.  J Am Acad Dermatol 45: 109-117.
Levy LL, Zeichner JA (2012) Management of acne scarring, Part II:  A comparative review of non-laser based, minimally invasive approaches.  Am J Clin Dermatol 13:331-340.
Shah SK, Alexis AF (2010) Acne in skin of color:  practical approaches to treatment.  J Dermatolog Treat 21:206-211.
阿尔斯特TS,西TB(1996)萎缩性面部痤疮疤痕具有高能量,脉冲二氧化碳激光换肤。皮肤科外科22:151-155。
Camirand A,杜塞J(下1997)针磨皮。审美普拉斯特外科21:48-51。
Fabbrocini G,Fardella N,Monfrecola A,PROIETTI我,Innocenzi D使用(2009)痤疮疤痕治疗皮肤针刺。临床实验皮肤病学杂志34:874-879。
Fabbrocini G,农齐亚塔MC,D'阿科V,德维塔V,洛迪G,Mauriello MC,帕斯托雷楼Monfrecola G(2010)痤疮疤痕:发病机制,分类和处理。皮肤科RES PRACT 2010:893080。
古德曼G(2003)发表痤疮疤痕:检讨。&#308;Cosmet激光疗法5:77-95。
古德曼GJ,男爵JA(2006)发布痤疮疤痕:一个定性全球疤痕分级系统。皮肤科外科32:1458年至1466年。
格雷伯EM,潭子EL,阿尔斯特TS(2008)副作用和点阵激光光热的并发症:961治疗经验。皮肤科外科34:
301-305。
雅各布CI,佛JS,卡米MS(2001)痤疮疤痕:一个分类体系和审查的治疗方案。&#308;上午科学院皮肤病学杂志45:109-117。
利维LL,Zeichner JA(2012)痤疮疤痕,第二部分的管理:非激光为基础的比较研究,微创的方法。牛J临床皮肤科杂志13:331-340。
沙阿SK,亚历克西斯AF(2010)痤疮的颜色皮肤:实用的治疗方法。&#308;Dermatolog治疗21:206-211。

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发表于 2015-5-31 13:55:25 | 显示全部楼层
版主中文英文通吃啊!看来你应该是治疗痘痘的专家。国内的文献满足不了你。

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这些其实都是平时查询资料的时候收集整理的,时不时的发一篇出来, 也可以让大家看到国内外,对于痤疮和痘坑修复治疗的观念。  详情 回复 发表于 2015-6-1 14:05
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 楼主| 发表于 2015-6-1 14:05:04 | 显示全部楼层
回头一笑 发表于 2015-5-31 13:55
版主中文英文通吃啊!看来你应该是治疗痘痘的专家。国内的文献满足不了你。

这些其实都是平时查询资料的时候收集整理的,时不时的发一篇出来,
也可以让大家看到国内外,对于痤疮和痘坑修复治疗的观念。


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